Interpol
2 September 2010



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DNA Profiling
Frequently asked questions about DNA profiling

 

  1. What is DNA profiling?
  2. What are the benefits of DNA profiling?
  3. What are the principles of DNA profiling?
  4. Are there any probable defence challenges to DNA profiling?
  5. Are there any efforts towards the standardisation and internationalisation of DNA profiling world-wide?
  6. Is INTERPOL also involved in these activities?
  7. What is the INTERPOL DNA profile Monitoring Expert Group (DNA MEG) about and what are its tasks?

 

 1. What is DNA profiling?
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DNA profiling is a process which begins when a minute sample of genetic material - DNA (deoxyribonucleic acid) - is taken from human tissue and ends when the sample is given a computerised numeric value in the form of a 'bar code'. Comparing a person's DNA profile with a DNA sample retrieved from the scene of a crime can eliminate innocent people, but can also provide a strong indication of guilt.


 2. What are the benefits of DNA profiling?
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The experience acquired by countries already using DNA profiling in their crime investigations shows that there are several important advantages to be gained:

  • rapid and absolute elimination of innocent suspects;
  • rapid identification of offenders with a very high degree of certainty;
  • reliability of evidence produced in court;
  • better administration of justice;
  • increased public confidence in the criminal justice system;
  • a deterrent effect on offenders with a concomitant decrease in crime;
  • cost-effectiveness in terms of investigation time saved.


 3. What are the principles of DNA profiling?
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The principle on which DNA profiling is based is relatively straightforward: a series of molecular biology techniques is used to determine the sizes of discrete DNA fragments that contain hypervariable target sequences. Because molecular biology is a new discipline with technical possibilities that are still expanding, it is hardly surprising that a variety of 'standard' techniques are used at each step in DNA profiling. The analysis principles, however, remain constant. They include:

  • collecting samples from the scene of a crime and from victims and suspects;
  • extracting and purifying DNA from all the samples;
  • cutting the DNA into fragments (with a 'restriction enzyme');
  • visualising the fragments;
  • analysing the resulting bank patterns by computer.

DNA profiling is a complicated process. As already mentioned, each sequential step involved in generating a DNA profile can be carried out in a variety of ways. Although they are all straightforward, and factors affecting them have been documented, each step is performed differently in different laboratories. Much of this variation is of little account, but in the present unregulated climate there remains a very real potential for generating a variety of anomalies.


 4. Are there any probable defence challenges to DNA profiling?
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Yes, the investigating officers and prosecutors using DNA profiling should be aware of several areas where the defence could challenge evidence successfully. The main points that could be raised are:

  • possible contamination of samples which could lead to a different interpretation of results or their invalidation;
  • comparison with an inadequate population sample size as the basis for the probability calculations;
  • improper sample handling or the unreliability of laboratory procedures.


 5. Are there any efforts towards the standardisation and internationalisation of DNA profiling world-wide?
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Yes, it is essential that standards be established and rules on accreditation and auditing applied at both national and international levels. Only if there is one will there be a possibility to exchange data internationally.

Europe seems to be a very active region from this point of view. The European DNA Profiling Group (EDNAP) was set up in 1988 and it has made considerable progress. The aim of this informal group is to facilitate the exchange of compatible DNA profiling data in order to allow European countries to make the best possible use of the opportunities provided by this technique. The European co-operation in this topic was reinforced and formalised by the involvement of the European Union (EU). Within this framework, there is a Working group on Police Co-operation, which deals also with DNA related topics. The society of forensic scientists is represented by the European Network of Forensic Science Institutes (ENFSI) Working Group on DNA Profiling.


 6. Is INTERPOL also involved in these activities?
Top

Yes, of course. The 25th Regional Conference (Warsaw, 29-31 May 1996) endorsed the revised European Business Plan, in which promoting good practice in the use of DNA profiling as an investigative technique is one of the main priorities. In order to implement this task, the INTERPOL European Committee decided at its 15th Meeting on 5 November 1996 to set up the INTERPOL European Working Party on DNA profiling.

The Final Report of the Interpol European Working Party on DNA profiling (new name now: DNA MEG) has been discussed by the 67th General Assembly Session in Cairo. Theworking group was advised to profit from the experience of other countries in the field ofDNA use in criminal investigations in order to get a global harmonisation. In this respect itwas agreed to invite representatives from all continents to join the DNA MEG.


 7. What is the INTERPOL DNA profile Monitoring Expert Group (DNA MEG) about and what are its tasks?
Top

The INTERPOL DNA MEG discusses the use of DNA profiling as an investigative technique and will make recommendations concerning the use of DNA in criminal investigations with a view to facilitating the worldwide use of this technique. The objective of the group is to act as an international point of reference facilitating the utilisation future development of DNA techniques. The recommendations will address following areas:

  • Investigation of crimes and incidents
  • Establishing protocols for the application of DNA
  • Data basing
  • Facilitate training

Other tasks are

  • Providing assistance and support to developing countries acting as a catalyst for the expansion of DNA applications
  • Widening co-operation with law enforcement agencies, international leading societies and institutions dealing with or working on DNA profiling
  • Getting a global overview about the trends in the sphere of DNA profiling
  • Organization of DNA related conferences and working meetings

Following Interpol member states are represented in the DNA MEG:

Argentina, Australia, Austria, Belgium, France, Norway, South Africa, Spain, United Kingdom and the USA.


The DNA MEG takes into consideration the work already done in this field by other fora dealing with or working on DNA profiling. The current members representing following international or national working groups before the DNA MEG:

AICEF-GITAD (Academica Iberoamericana de Criminalistica y Estudios Forenses)
CODIS (The FBI Laboratory’s Combined DNA Index System)
EDNAP (European DNA Profiling group),
ENFSI (European Network on Forensic Science Institutes)
FBI (Federal Bureau of Investigation)
FSS (Forensic Science Service in UK)
GEP-ISFH (Spanish and Portuguese working group - International Society for Forensic Haemogenetics)
Interpol WG on DVI (Working Group on Disaster Victim Identification)
ISFG (International Society for Forensic Genetics)
NCIS (National Criminal Intelligence Service in UK)
NDIS (The FBI’s National DNA Index System)
NIFS (National Institute of Forensic Science - Australia)
PCWG (Police Co-operation in the European Union)
SMANZFL (Senior Managers Australian and New Zealand Forensic Laboratories)
SWGDAM (Scientific Working Group on DNA Analysis Methods)

 

Updated April 2000

Last modified on 19 Sep 2002 
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